The Intestinal T Cell Response to α-Gliadin in Adult Celiac Disease Is Focused on a Single Deamidated Glutamine Targeted by Tissue Transglutaminase

The great majority of patients that are intolerant of wheat gluten protein due to celiac disease (CD) are human histocompatibility leukocyte antigen (HLA)-DQ2(+), and the remaining few normally express HLA-DQ8. These two class II molecules are chiefly responsible for the presentation of gluten pepti...

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Autors principals: Arentz-Hansen, Helene, Körner, Roman, Molberg, Øyvind, Quarsten, Hanne, Vader, Willemijn, Kooy, Yvonne M.C., Lundin, Knut E.A., Koning, Frits, Roepstorff, Peter, Sollid, Ludvig M., McAdam, Stephen N.
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2000
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2195837/
https://ncbi.nlm.nih.gov/pubmed/10684852
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