Absence of γ-Interferon–inducible Lysosomal Thiol Reductase in Melanomas Disrupts T Cell Recognition of Select Immunodominant Epitopes

Long-lasting tumor immunity requires functional mobilization of CD8(+) and CD4(+) T lymphocytes. CD4(+) T cell activation is enhanced by presentation of shed tumor antigens by professional antigen-presenting cells (APCs), coupled with display of similar antigenic epitopes by major histocompatibility...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Haque, M. Azizul, Li, Ping, Jackson, Sheila K., Zarour, Hassane M., Hawes, John W., Phan, Uyen T., Maric, Maja, Cresswell, Peter, Blum, Janice S.
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Rockefeller University Press 2002
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193747/
https://ncbi.nlm.nih.gov/pubmed/12021307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20011853
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk