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c-Jun NH(2)-Terminal Kinase (JNK)1 and JNK2 Signaling Pathways Have Divergent Roles in CD8(+) T Cell–mediated Antiviral Immunity

c-Jun NH(2)-terminal kinases (JNK) play important roles in T helper cell (Th) proliferation, differentiation, and maintenance of Th1/Th2 polarization. To determine whether JNKs are involved in antiviral T cell immunity, and whether JNK1 and JNK2 bear biological differences, we investigated the immun...

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Detalhes bibliográficos
Main Authors: Arbour, Nathalie, Naniche, Denise, Homann, Dirk, Davis, Roger J., Flavell, Richard A., Oldstone, Michael B.A.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193720/
https://ncbi.nlm.nih.gov/pubmed/11927625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20011481
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