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Sialic Acid Binding Domains of CD22 Are Required For Negative Regulation of B Cell Receptor Signaling
CD22, a negative regulator of B cell antigen receptor signaling, binds glycoconjugates terminating in α2, 6 sialic acid. The physiological ligand(s) for CD22 remain unknown. We asked whether the sialic acid binding domains are necessary for CD22 to function as a negative regulator. We generated two...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Rockefeller University Press
2002
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2193702/ https://ncbi.nlm.nih.gov/pubmed/11994425 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20011796 |
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