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Processing of Mycobacterium tuberculosis Antigen 85B Involves Intraphagosomal Formation of Peptide–Major Histocompatibility Complex II Complexes and Is Inhibited by Live Bacilli that Decrease Phagosome Maturation

Mycobacterium tuberculosis (MTB) inhibits phagosomal maturation to promote its survival inside macrophages. Control of MTB infection requires CD4 T cell responses and major histocompatibility complex (MHC) class II (MHC-II) processing of MTB antigens (Ags). To investigate phagosomal processing of MT...

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Библиографические подробности
Главные авторы: Ramachandra, Lakshmi, Noss, Erika, Boom, W. Henry, Harding, Clifford V.
Формат: Artigo
Язык:Inglês
Опубликовано: The Rockefeller University Press 2001
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193679/
https://ncbi.nlm.nih.gov/pubmed/11714749
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