Deletion of Calcineurin and Myocyte Enhancer Factor 2 (MEF2) Binding Domain of Cabin1 Results in Enhanced Cytokine Gene Expression in T Cells

Cabin1 binds calcineurin and myocyte enhancer factor 2 (MEF2) through its COOH-terminal region. In cell lines, these interactions were shown to inhibit calcineurin activity after T cell receptor (TCR) signaling and transcriptional activation of Nur77 by MEF2. The role of these interactions under phy...

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Hlavní autoři: Esau, Christine, Boes, Marianne, Youn, Hong-Duk, Tatterson, Lisa, Liu, Jun O., Chen, Jianzhu
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2001
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193671/
https://ncbi.nlm.nih.gov/pubmed/11714752
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