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Synaptotagmin II Negatively Regulates Ca(2+)-triggered Exocytosis of Lysosomes in Mast Cells
Synaptotagmins (Syts) I and II are believed to act as Ca(2+) sensors in the control of neurotransmission. Here we demonstrate that mast cells express Syt II in their lysosomal fraction. We further show that activation of mast cells by either aggregation of FcεRI or by Ca(2+) ionophores results in ex...
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| Auteurs principaux: | , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The Rockefeller University Press
1999
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2193646/ https://ncbi.nlm.nih.gov/pubmed/10330444 |
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