Low-level Hypermutation in T Cell–independent Germinal Centers Compared with High Mutation Rates Associated with T Cell–dependent Germinal Centers

Exceptionally germinal center formation can be induced without T cell help by polysaccharide-based antigens, but these germinal centers involute by massive B cell apoptosis at the time centrocyte selection starts. This study investigates whether B cells in germinal centers induced by the T cell–inde...

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Detalhes bibliográficos
Main Authors: Toellner, Kai-Michael, Jenkinson, William E., Taylor, Dale R., Khan, Mahmood, Sze, Daniel M.-Y., Sansom, David M., Vinuesa, Carola G., MacLennan, Ian C.M.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2002
Assuntos:
Brief Definitive Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193598/
https://ncbi.nlm.nih.gov/pubmed/11828014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20011112
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