Generation of Tumor-associated Cytotoxic T Lymphocytes Requires Interleukin 4 from CD8(+) T Cells

Activation of tumor-associated CD8(+) cytotoxic T lymphocytes (CTLs) often requires antigen representation, e.g., by dendritic cells (DCs), and CD4(+) T cell help. Previously, we showed that CTL-mediated tumor immunity required interleukin 4 (IL-4) during the immunization but not effector phase. To...

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Main Authors: Schüler, Thomas, Kammertoens, Thomas, Preiss, Susanne, Debs, Pierre, Noben-Trauth, Nancy, Blankenstein, Thomas
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 2001
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Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193572/
https://ncbi.nlm.nih.gov/pubmed/11748278
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