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Antigen Is Required for the Activation of Effector Activities, whereas Interleukin 2 Is Required for the Maintenance of Memory in Ovalbumin-specific, CD8(+) Cytotoxic T Lymphocytes

The mechanisms that maintain memory in T cells are not completely understood. We have investigated the role of antigen and interleukin (IL)-2 in the growth and maintenance of CD8(+) T cells using a cytolytic T cell line specific for ovalbumin (OVA)(257-264) presented by H-2K(b). This line does not s...

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Detalhes bibliográficos
Main Authors: Ke, Yong, Ma, Hakling, Kapp, Judith A.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2199192/
https://ncbi.nlm.nih.gov/pubmed/9419210
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