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Splenic T Zone Development Is B Cell Dependent

The factors regulating growth and patterning of the spleen are poorly defined. We demonstrate here that spleens from B cell–deficient mice have 10-fold reduced expression of the T zone chemokine, CCL21, a threefold reduction in T cell and dendritic cell (DC) numbers, and reduced expression of the T...

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Detalhes bibliográficos
Main Authors: Ngo, Vu N., Cornall, Richard J., Cyster, Jason G.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193532/
https://ncbi.nlm.nih.gov/pubmed/11733579
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