Processing of a Multiple Membrane Spanning Epstein-Barr Virus Protein for Cd8(+)T Cell Recognition Reveals a Proteasome-Dependent, Transporter Associated with Antigen Processing–Independent Pathway

Epstein-Barr virus (EBV) latent membrane protein (LMP)2 is a multiple membrane spanning molecule which lacks ectodomains projecting into the lumen of the endoplasmic reticulum (ER). Human CD8(+) cytotoxic T lymphocytes (CTL)s recognize a number of epitopes within LMP2. Assays with epitope-specific C...

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Detalhes bibliográficos
Main Authors: Lautscham, Georg, Mayrhofer, Sabine, Taylor, Graham, Haigh, Tracey, Leese, Alison, Rickinson, Alan, Blake, Neil
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2001
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193515/
https://ncbi.nlm.nih.gov/pubmed/11602636
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