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Homeostasis of Peripheral B Cells in the Absence of B Cell Influx from the Bone Marrow

To study homeostasis of peripheral B lymphocytes in the absence of B cell influx from the bone marrow, we generated a mouse mutant in which the recombination-activating gene (RAG)-2 can be inducibly deleted. When RAG-2 was deleted at the age of 8–10 wk, splenic naive follicular B cells were graduall...

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Библиографические подробности
Главные авторы: Hao, Zhenyue, Rajewsky, Klaus
Формат: Artigo
Язык:Inglês
Опубликовано: The Rockefeller University Press 2001
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193512/
https://ncbi.nlm.nih.gov/pubmed/11602643
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