Maturation of Dendritic Cells Is Accompanied by Rapid Transcriptional Silencing of Class II Transactivator (Ciita) Expression

Cell surface expression of major histocompatibility complex class II (MHCII) molecules is increased during the maturation of dendritic cells (DCs). This enhances their ability to present antigen and activate naive CD4(+) T cells. In contrast to increased cell surface MHCII expression, de novo biosyn...

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Main Authors: Landmann, Salomé, Mühlethaler-Mottet, Annick, Bernasconi, Luca, Suter, Tobias, Waldburger, Jean-Marc, Masternak, Krzysztof, Arrighi, Jean-François, Hauser, Conrad, Fontana, Adriano, Reith, Walter
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 2001
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Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193505/
https://ncbi.nlm.nih.gov/pubmed/11514596
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