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Requirement for Transforming Growth Factor β1 in Controlling T Cell Apoptosis
Transforming growth factor (TGF)-β1, a potent immunoregulatory molecule, was found to control the life and death decisions of T lymphocytes. Both thymic and peripheral T cell apoptosis was increased in mice lacking TGF-β1 (TGF-β1(−/−)) compared with wild-type littermates. Engagement of the T cell re...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2193497/ https://ncbi.nlm.nih.gov/pubmed/11514601 |
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