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Deficiency of Small Gtpase Rac2 Affects T Cell Activation

Rac2 is a hematopoietic-specific GTPase acting as a molecular switch to mediate both transcriptional activation and cell morphological changes. We have examined the effect of Rac2 deficiency during T cell activation. In Rac2(−/−) T cells, proliferation was reduced upon stimulation with either plate-...

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Detalhes bibliográficos
Main Authors: Yu, Hong, Leitenberg, Dave, Li, Baiyong, Flavell, Richard A.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193485/
https://ncbi.nlm.nih.gov/pubmed/11581314
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