Staphylococcus aureus Resistance to Human Defensins and Evasion of Neutrophil Killing via the Novel Virulence Factor Mprf Is Based on Modification of Membrane Lipids with l-Lysine

Defensins, antimicrobial peptides of the innate immune system, protect human mucosal epithelia and skin against microbial infections and are produced in large amounts by neutrophils. The bacterial pathogen Staphylococcus aureus is insensitive to defensins by virtue of an unknown resistance mechanism...

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Main Authors: Peschel, Andreas, Jack, Ralph W., Otto, Michael, Collins, L. Vincent, Staubitz, Petra, Nicholson, Graeme, Kalbacher, Hubert, Nieuwenhuizen, Willem F., Jung, Günther, Tarkowski, Andrej, van Kessel, Kok P.M., van Strijp, Jos A.G.
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 2001
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Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193429/
https://ncbi.nlm.nih.gov/pubmed/11342591
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