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Human Cd25(+)Cd4(+) T Regulatory Cells Suppress Naive and Memory T Cell Proliferation and Can Be Expanded in Vitro without Loss of Function
Active suppression by T regulatory (Tr) cells plays an important role in the downregulation of T cell responses to foreign and self-antigens. Mouse CD4(+) Tr cells that express CD25 possess remarkable suppressive activity in vitro and in autoimmune disease models in vivo. Thus far, the existence of...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
The Rockefeller University Press
2001
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2193376/ https://ncbi.nlm.nih.gov/pubmed/11390436 |
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