Histone Acetylation Determines the Developmentally Regulated Accessibility for T Cell Receptor γ Gene Recombination

Variable/diversity/joining (V[D]J) recombination of the T cell receptor (TCR) and immunoglobulin (Ig) genes is regulated by chromatin accessibility of the target locus to the recombinase in a lineage- and stage-specific manner. Histone acetylation has recently been proposed as a molecular mechanism...

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Autores principales: Agata, Yasutoshi, Katakai, Tomoya, Ye, Sang-Kyu, Sugai, Manabu, Gonda, Hiroyuki, Honjo, Tasuku, Ikuta, Koichi, Shimizu, Akira
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 2001
Materias:
Brief Definitive Report
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193365/
https://ncbi.nlm.nih.gov/pubmed/11283160
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