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The Notch Ligand Jagged-1 Represents a Novel Growth Factor of Human Hematopoietic Stem Cells

The Notch ligand, Jagged-1, plays an essential role in tissue formation during embryonic development of primitive organisms. However, little is known regarding the role of Jagged-1 in the regulation of tissue-specific stem cells or its function in humans. Here, we show that uncommitted human hematop...

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Autors principals: Karanu, Frances N., Murdoch, Barbara, Gallacher, Lisa, Wu, Dongmei M., Koremoto, Masahide, Sakano, Seiji, Bhatia, Mickie
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2000
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193352/
https://ncbi.nlm.nih.gov/pubmed/11067884
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