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C-Reactive Protein Binds to Apoptotic Cells, Protects the Cells from Assembly of the Terminal Complement Components, and Sustains an Antiinflammatory Innate Immune Response: Implications for Systemic Autoimmunity

C-reactive protein (CRP) is a serum protein that is massively induced as part of the innate immune response to infection and tissue injury. As CRP has been detected in damaged tissues and is known to activate complement, we assessed whether apoptotic lymphocytes bound CRP and determined the effect o...

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Библиографические подробности
Главные авторы: Gershov, Debra, Kim, SunJung, Brot, Nathan, Elkon, Keith B.
Формат: Artigo
Язык:Inglês
Опубликовано: The Rockefeller University Press 2000
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193350/
https://ncbi.nlm.nih.gov/pubmed/11067883
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