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Natural Resistance to Intracellular Infections: Natural Resistance–Associated Macrophage Protein 1 (Nramp1) Functions as a Ph-Dependent Manganese Transporter at the Phagosomal Membrane
Mutations at the natural resistance–associated macrophage protein 1 (Nramp1) locus cause susceptibility to infection with antigenically unrelated intracellular pathogens. Nramp1 codes for an integral membrane protein expressed in the lysosomal compartment of macrophages, and is recruited to the memb...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The Rockefeller University Press
2000
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2193348/ https://ncbi.nlm.nih.gov/pubmed/11067873 |
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