Natural Resistance to Intracellular Infections: Natural Resistance–Associated Macrophage Protein 1 (Nramp1) Functions as a Ph-Dependent Manganese Transporter at the Phagosomal Membrane

Mutations at the natural resistance–associated macrophage protein 1 (Nramp1) locus cause susceptibility to infection with antigenically unrelated intracellular pathogens. Nramp1 codes for an integral membrane protein expressed in the lysosomal compartment of macrophages, and is recruited to the memb...

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Main Authors: Jabado, Nada, Jankowski, Andrzej, Dougaparsad, Samuel, Picard, Virginie, Grinstein, Sergio, Gros, Philippe
Formáid: Artigo
Teanga:Inglês
Foilsithe: The Rockefeller University Press 2000
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Original Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193348/
https://ncbi.nlm.nih.gov/pubmed/11067873
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