An Alternative Open Reading Frame of the Human Macrophage Colony-Stimulating Factor Gene Is Independently Translated and Codes for an Antigenic Peptide of 14 Amino Acids Recognized by Tumor-Infiltrating Cd8 T Lymphocytes

We show that cytotoxic T lymphocytes (CTLs) infiltrating a kidney tumor recognize a peptide encoded by an alternative open reading frame (ORF) of the macrophage colony-stimulating factor (M-CSF) gene. Remarkably, this alternative ORF, which is translated in many tumors concurrently with the major OR...

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Main Authors: Probst-Kepper, Michael, Stroobant, Vincent, Kridel, Robert, Gaugler, Béatrice, Landry, Claire, Brasseur, Francis, Cosyns, Jean-Pierre, Weynand, Birgit, Boon, Thierry, Van den Eynde, Benoit J.
פורמט: Artigo
שפה:Inglês
יצא לאור: The Rockefeller University Press 2001
נושאים:
Original Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193327/
https://ncbi.nlm.nih.gov/pubmed/11369790
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