Nuclear Factor of Activated T Cells Transcription Factor Nfatp Controls Superantigen-Induced Lethal Shock

Tumor necrosis factor α (TNF-α) is the key mediator of superantigen-induced T cell lethal shock. Here, we show that nuclear factor of activated T cells transcription factor, NFATp, controls susceptibility to superantigen-induced lethal shock in mice through its activation of TNF-α gene transcription...

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Bibliographic Details
Main Authors: Tsytsykova, Alla V., Goldfeld, Anne E.
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2000
Subjects:
Brief Definitive Report
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193238/
https://ncbi.nlm.nih.gov/pubmed/10952728
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