Interferon Regulatory Factor (Irf)-1 and Irf-2 Regulate Interferon γ–Dependent Cyclooxygenase 2 Expression

Cyclooxygenases (Cox) are rate-limiting enzymes that initiate the conversion of arachidonic acid to prostanoids. Cox-2 is the inducible isoform that is upregulated by proinflammatory agents, initiating many prostanoid-mediated pathological aspects of inflammation. In this study, we demonstrate that...

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Главные авторы: Blanco, Jorge C. G., Contursi, Cristina, Salkowski, Cindy A., DeWitt, David L., Ozato, Keiko, Vogel, Stefanie N.
Формат: Artigo
Язык:Inglês
Опубликовано: The Rockefeller University Press 2000
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Original Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193204/
https://ncbi.nlm.nih.gov/pubmed/10859338
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