Anti–Interleukin 10 Receptor Monoclonal Antibody Is an Adjuvant for T Helper Cell Type 1 Responses to Soluble Antigen Only in the Presence of Lipopolysaccharide

Soluble foreign antigen usually leads to a transient clonal expansion of antigen-specific T cells followed by the deletion and/or functional inactivation of the cells. As interleukin (IL)-10 is a key immunoregulatory cytokine, we questioned whether neutralization of IL-10 during priming with soluble...

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Hlavní autoři: Castro, Antonio G., Neighbors, Margaret, Hurst, Stephen D., Zonin, Francesca, Silva, Regina A., Murphy, Erin, Liu, Yong-Jun, O'Garra, Anne
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2000
Témata:
Brief Definitive Report
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193194/
https://ncbi.nlm.nih.gov/pubmed/11085755
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