The Role of Virus-Specific Cd8(+) Cells in Liver Damage and Viral Control during Persistent Hepatitis B Virus Infection

Hepatitis B virus (HBV) is a noncytopathic virus, and the recognition of infected hepatocytes by HBV-specific CD8 cells has been assumed to be the central mechanism causing both liver damage and virus control. To understand the role of cytotoxic T cells in the pathogenesis of HBV infection, we used...

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Hauptverfasser: Maini, Mala K., Boni, Carolina, Lee, Chun Kyon, Larrubia, Juan R., Reignat, Stephanie, Ogg, Graham S., King, Abigail S., Herberg, Jethro, Gilson, Richard, Alisa, Akeem, Williams, Roger, Vergani, Diego, Naoumov, Nikolai V., Ferrari, Carlo, Bertoletti, Antonio
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2000
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193131/
https://ncbi.nlm.nih.gov/pubmed/10770795
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