Longitudinal Analysis of CD8(+) T Cells Specific for Structural and Nonstructural Hepatitis B Virus Proteins in Patients with Chronic Hepatitis B: Implications for Immunotherapy

The cytotoxic T-cell response in chronic hepatitis B virus (HBV) infection has been described as weak and mono- or oligospecific in comparison to the more robust virus-specific T-cell response present in resolved infection. However, chronic hepatitis B is a heterogeneous disease with markedly variab...

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Autors principals: Webster, George J. M., Reignat, Stephanie, Brown, David, Ogg, Graham S., Jones, Louise, Seneviratne, Suranjith L., Williams, Roger, Dusheiko, Geoffrey, Bertoletti, Antonio
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2004
Matèries:
Pathogenesis and Immunity
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC415806/
https://ncbi.nlm.nih.gov/pubmed/15140968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.11.5707-5719.2004
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