Neutrophil-specific Granule Deficiency Results from a Novel Mutation with Loss of Function of the Transcription Factor CCAAT/Enhancer Binding Protein ε

Neutrophil-specific granule deficiency (SGD) is a rare disorder characterized by recurrent pyogenic infections, defective neutrophil chemotaxis and bactericidal activity, and lack of neutrophil secondary granule proteins. CCAAT/enhancer binding protein (C/EBP)ε, a member of the leucine zipper family...

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Autores principales: Lekstrom-Himes, Julie A., Dorman, Susan E., Kopar, Piroska, Holland, Steven M., Gallin, John I.
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 1999
Materias:
Brief Definitive Reports
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193089/
https://ncbi.nlm.nih.gov/pubmed/10359588
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