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An Inhibitor of Exported Mycobacterium tuberculosis Glutamine Synthetase Selectively Blocks the Growth of Pathogenic Mycobacteria in Axenic Culture and in Human Monocytes: Extracellular Proteins as Potential Novel Drug Targets

Mycobacterium tuberculosis and other pathogenic mycobacteria export abundant quantities of proteins into their extracellular milieu when growing either axenically or within phagosomes of host cells. One major extracellular protein, the enzyme glutamine synthetase, is of particular interest because o...

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Bibliografiska uppgifter
Huvudupphovsmän: Harth, Günter, Horwitz, Marcus A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Rockefeller University Press 1999
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193054/
https://ncbi.nlm.nih.gov/pubmed/10224282
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