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The Cyclin-dependent Kinase Cdk2 Regulates Thymocyte Apoptosis

Aberrant activation of cell cycle molecules has been postulated to play a role in apoptosis (“catastrophic cell cycle”). Here we show that in noncycling developing thymocytes, the cyclin- dependent kinase Cdk2 is activated in response to all specific and nonspecific apoptotic stimuli tested, includi...

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Detalhes bibliográficos
Main Authors: Hakem, Anne, Sasaki, Takehiko, Kozieradzki, Ivona, Penninger, Josef M.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193040/
https://ncbi.nlm.nih.gov/pubmed/10075979
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