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The Avidity Spectrum of  T Cell Receptor Interactions Accounts for T Cell Anergy in a Double Transgenic Model

The mechanism of self-tolerance in the CD4(+) T cell compartment was examined in a double transgenic (Tg) model in which T cell receptor (TCR)-α/β Tg mice with specificity for the COOH-terminal peptide of moth cytochrome c in association with I-E(k) were crossed with antigen Tg mice. Partial deletio...

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Detalles Bibliográficos
Main Authors: Girgis, Laila, Davis, Mark M., de St. Groth, Barbara Fazekas
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 1999
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2192997/
https://ncbi.nlm.nih.gov/pubmed/9892609
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