Mitochondrial Release of Caspase-2 and -9 during the Apoptotic Process

The barrier function of mitochondrial membranes is perturbed early during the apoptotic process. Here we show that the mitochondria contain a caspase-like enzymatic activity cleaving the caspase substrate Z-VAD.afc, in addition to three biological activities previously suggested to participate in th...

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Hlavní autoři: Susin, Santos A., Lorenzo, Hans K., Zamzami, Naoufal, Marzo, Isabel, Brenner, Catherine, Larochette, Nathanael, Prévost, Marie-Christine, Alzari, Pedro M., Kroemer, Guido
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 1999
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2192979/
https://ncbi.nlm.nih.gov/pubmed/9892620
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