Macrophage Microbicidal Mechanisms In Vivo: Reactive Nitrogen versus Oxygen Intermediates in the Killing of Intracellular Visceral Leishmania donovani

To determine the relative contributions of respiratory burst–derived reactive oxygen intermediates (ROI) versus reactive nitrogen intermediates (RNI) to macrophage-mediated intracellular host defense, mice genetically deficient in these mechanisms were challenged with Leishmania donovani, a protozoa...

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Bibliographic Details
Main Authors: Murray, Henry W., Nathan, Carl F.
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 1999
Subjects:
Brief Definitive Reports
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2192937/
https://ncbi.nlm.nih.gov/pubmed/9989990
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