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Macrophage Microbicidal Mechanisms In Vivo: Reactive Nitrogen versus Oxygen Intermediates in the Killing of Intracellular Visceral Leishmania donovani

To determine the relative contributions of respiratory burst–derived reactive oxygen intermediates (ROI) versus reactive nitrogen intermediates (RNI) to macrophage-mediated intracellular host defense, mice genetically deficient in these mechanisms were challenged with Leishmania donovani, a protozoa...

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Detalles Bibliográficos
Main Authors: Murray, Henry W., Nathan, Carl F.
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 1999
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2192937/
https://ncbi.nlm.nih.gov/pubmed/9989990
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