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C-reactive Protein: A Physiological Activator of Interleukin 6 Receptor Shedding

The soluble interleukin 6 receptor (sIL-6R) circulates at elevated levels in various diseases. This suggests that inflammatory mediators control sIL-6R release. Through examination of human neutrophils, it was found that the acute phase reactant C-reactive protein (CRP) activates a threefold increas...

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Detalhes bibliográficos
Main Authors: Jones, Simon A., Novick, Daniela, Horiuchi, Sankichi, Yamamoto, Naoki, Szalai, Alexander J., Fuller, Gerald M.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2192917/
https://ncbi.nlm.nih.gov/pubmed/9927522
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