Role of Interleukin-6 in Mortality from and Physiologic Response to Sepsis

Previous studies have suggested that interleukin-6 (IL-6) serves as both a marker and a mediator for the severity of sepsis. We tested whether interleukin 6 knockout (IL-6KO) mice were more susceptible to sepsis mortality induced by cecal ligation and puncture. IL-6KO and wild-type (WT) mice were su...

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Detalhes bibliográficos
Main Authors: Remick, Daniel G., Bolgos, Gerald, Copeland, Shannon, Siddiqui, Javed
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Host Response and Inflammation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1087378/
https://ncbi.nlm.nih.gov/pubmed/15845478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.5.2751-2757.2005
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