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Dual interaction of the malaria circumsporozoite protein with the low density lipoprotein receptor-related protein (LRP) and heparan sulfate proteoglycans

Speed and selectivity of hepatocyte invasion by malaria sporozoites have suggested a receptor-mediated mechanism and the specific interaction of the circumsporozoite (CS) protein with liver-specific heparan sulfate proteoglycans (HSPGs) has been implicated in the targeting to the liver. Here we show...

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Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 1996
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2192891/
https://ncbi.nlm.nih.gov/pubmed/8920859
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