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Inactivation of the IL-6 gene prevents development of multicentric Castleman's disease in C/EBP beta-deficient mice
Castleman's disease is a lymphoproliferative disorder thought to be related to deregulated production of IL-6. We have previously shown that mice lacking the trans-acting factor C/EBP beta, a transcriptional regulator of IL-6 and a mediator of IL-6 intracellular signaling, develop a pathology n...
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| Format: | Artigo |
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| Sprache: | Inglês |
| Veröffentlicht: |
The Rockefeller University Press
1996
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2192807/ https://ncbi.nlm.nih.gov/pubmed/8879230 |
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