HHV-8–encoded viral IL-6 collaborates with mouse IL-6 in the development of multicentric Castleman disease in mice

Human herpes virus 8 (HHV-8) or Kaposi sarcoma-associated herpes virus is the etiologic agent of Kaposi sarcoma, primary effusion lymphoma, and plasma cell-type multicentric Castleman disease (MCD). HHV-8 encodes a viral homolog of human IL-6, called viral IL-6 (vIL-6), which does not require the ce...

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Main Authors: Suthaus, Jan, Stuhlmann-Laeisz, Christiane, Tompkins, Van S., Rosean, Timothy R., Klapper, Wolfram, Tosato, Giovanna, Janz, Siegfried, Scheller, Jürgen, Rose-John, Stefan
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Hematology 2012
Assuntos:
Immunobiology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3370672/
https://ncbi.nlm.nih.gov/pubmed/22490805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-09-377705
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