Role of the Pi3k Regulatory Subunit in the Control of Actin Organization and Cell Migration

Cell migration represents an important cellular response that utilizes cytoskeletal reorganization as its driving force. Here, we describe a new signaling cascade linking PDGF receptor stimulation to actin rearrangements and cell migration. We demonstrate that PDGF activates Cdc42 and its downstream...

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Detalhes bibliográficos
Main Authors: Jiménez, Concepción, Portela, Rosario Armas, Mellado, Mario, Rodríguez-Frade, Jose Miguel, Collard, John, Serrano, Antonio, Martínez-A, Carlos, Avila, Jesus, Carrera, Ana C.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2000
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2192656/
https://ncbi.nlm.nih.gov/pubmed/11038173
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