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The SH3 domain of p56lck binds to proline-rich sequences in the cytoplasmic domain of CD2

CD2, a cell surface glycoprotein expressed on T cells and natural killer cells, can couple to signaling pathways that result in T cell proliferation. An Src-like protein tyrosine kinase, p56lck, coprecipitates with CD2, and perturbation of CD2 by monoclonal antibodies results in an increase in the a...

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Détails bibliographiques
Format: Artigo
Langue:Inglês
Publié: The Rockefeller University Press 1996
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2192399/
https://ncbi.nlm.nih.gov/pubmed/8551220
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