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T cells from late tumor-bearing mice express normal levels of p56lck, p59fyn, ZAP-70, and CD3 zeta despite suppressed cytolytic activity

Loss of T cell-associated signal transduction molecules has recently been implicated in immune suppression in tumor-bearing hosts. In the present study, we have examined this and related phenomenon extensively in a large number of tumor-bearing mice, analyzed individually. Splenic T cells from tumor...

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Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 1995
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2192279/
https://ncbi.nlm.nih.gov/pubmed/7561676
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