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Interaction between CD8 and major histocompatibility complex (MHC) class I mediated by multiple contact surfaces that include the alpha 2 and alpha 3 domains of MHC class I
The cell surface glycoprotein CD8 functions as a coreceptor with the TCR on cytotoxic T lymphocytes. Mutational analysis of the binding site of CD8 for MHC class I predicted that distinct surfaces of CD8 would interact with both the alpha 2 and alpha 3 domains of class I. Using a cell-cell adhesion...
Kaydedildi:
| Materyal Türü: | Artigo |
|---|---|
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
The Rockefeller University Press
1995
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2192184/ https://ncbi.nlm.nih.gov/pubmed/7595198 |
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