Tumor Suppressor Pten Inhibits Nuclear Accumulation of β-Catenin and T Cell/Lymphoid Enhancer Factor 1–Mediated Transcriptional Activation

β-Catenin is a protein that plays a role in intercellular adhesion as well as in the regulation of gene expression. The latter role of β-catenin is associated with its oncogenic properties due to the loss of expression or inactivation of the tumor suppressor adenomatous polyposis coli (APC) or mutat...

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Hauptverfasser: Persad, Sujata, A.Troussard, Armelle, McPhee, Timothy R., Mulholland, David J., Dedhar, Shoukat
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2001
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2192018/
https://ncbi.nlm.nih.gov/pubmed/11402061
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