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T cell receptor-mediated signaling events in CD4+CD8+ thymocytes undergoing thymic selection: requirement of calcineurin activation for thymic positive selection but not negative selection
The goal of this study was to identify the differences of intracellular signals between the processes of thymic positive and negative selection. The activation of calcineurin, a calcium- and calmodulin- dependent phosphatase, is known to be an essential event in T cell activation via the T cell rece...
Uloženo v:
| Médium: | Artigo |
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| Jazyk: | Inglês |
| Vydáno: |
The Rockefeller University Press
1995
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2191909/ https://ncbi.nlm.nih.gov/pubmed/7532685 |
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