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Genetic requirement for Ras in the transformation of fibroblasts and hematopoietic cells by the Bcr-Abl oncogene
To determine the functional importance of Ras in transformation by Abl oncogenes, we used a genetic approach to measure the effect of impaired Ras activity on the ability of Bcr-Abl or v-Abl to transform cells. Expression of the catalytic domain of the GTPase activating protein for Ras (Gap C termin...
Tallennettuna:
| Aineistotyyppi: | Artigo |
|---|---|
| Kieli: | Inglês |
| Julkaistu: |
The Rockefeller University Press
1995
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2191855/ https://ncbi.nlm.nih.gov/pubmed/7807010 |
| Tagit: |
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