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Humoral immune responses in CD40 ligand-deficient mice

Individuals with X-linked hyper-IgM syndrome fail to express functional CD40 ligand (CD40L) and, as a consequence, are incapable of mounting protective antibody responses to opportunistic bacterial infections. To address the role of CD40L in humoral immunity, we created, through homologous recombina...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 1994
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2191723/
https://ncbi.nlm.nih.gov/pubmed/7964465
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