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Leukocyte common antigen (CD45) is required for immunoglobulin E- mediated degranulation of mast cells
We demonstrate using primary mast cell cultures derived from wild-type and CD45-deficient mice that mast cell triggering through the high- affinity immunoglobulin E (IgE) receptor requires the cell surface tyrosine phosphatase CD45. Unlike wild-type cells, cross-linking of surface-bound IgE in mast...
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| Formato: | Artigo |
|---|---|
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
1994
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2191589/ https://ncbi.nlm.nih.gov/pubmed/8046327 |
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